Role of Environmental Chemical Exposures in the Development of Obesity, Type 2 Diabetes and Metabolic Syndrome (R21)

Role of Environmental Chemical Exposures in the Development of Obesity, Type 2 Diabetes and Metabolic Syndrome (R21)

Purpose: This Funding Opportunity Announcement (FOA), issued by the National Institute of Environmental Health Sciences (NIEHS), encourages grant applications to understand the role of environmental chemical exposures in the development of obesity, type 2 diabetes and/or metabolic syndrome. Applications must link an environmental exposure to the increased incidence of weight gain, type 2 diabetes and aspects of metabolic syndrome in animal models or human studies. While any exposure window is acceptable it is anticipated that the most sensitive time for exposures to affect the disease outcomes will be during development e.g., in utero and/or neonatal or early childhood. For human studies developmental exposures (in utero and early childhood) should be linked to early biomarkers of disease onset. Animal studies should focus on identifying new environmental chemicals that alter weight gain, insulin sensitivity and glucose tolerance and altered lipid metabolism indicative of obesity, type 2 diabetes and/or metabolic syndrome.
Receipt Date: Cycle Due Dates (new submission): Feb. 16, June 16, Oct. 16
Expires Sept. 8, 2015
Total Awards: Application budgets are limited to $275,000 in direct costs over 2 years, with no more than $200,000 in direct costs allowed in any single year.
Eligibility: Any individual(s) with the skills, knowledge, and resources necessary to carry out the proposed research as the Program Director/Principal Investigator (PD/PI) is invited to work with his/her organization to develop an application for support. Individuals from underrepresented racial and ethnic groups as well as individuals with disabilities are always encouraged to apply for NIH support.
Link: http://grants.nih.gov/grants/guide/pa-files/PA-12-184.html
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