Study of obese family leads to CEP19 gene discovery

Nov. 21, 2013, HealthDay

Researchers report that they have identified a gene that is tied to severe obesity.

They say their findings could lead to new treatments for obesity.

The team studied an Israeli Arab family whose members were severely obese. They found that the family members had a mutation in a gene that produces a protein called CEP19.

When the researchers deleted this gene in mice, the rodents became obese and developed diabetes. They also had increased appetites and burned less energy.

Scientists note, however, that research done in animals often fails to produce similar results in humans. Continue reading